The greatest enemy of knowledge is not ignorance, it is the illusion of knowledge

This quote by the American historian Daniel Boorstin is becoming increasingly relevant also in medical research. Nowadays, it seems to be much more common than one or two decades ago that authors confuse cohort studies with case-control studies, cumulative incidence with incidence density, hazard ratios with odds ratios, etc., etc. It is paradoxical that the increased accessibility of information with Internet (and the easiness with which the definition of methodological terms can be checked) comes, in Rumsfeldian terms, with a reduction of the known unknown and a corresponding growth of the unknown unknown.